От Skvortsov
К Паршев
Дата 12.04.2020 09:20:17
Рубрики Современность;

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>>К первоначальному азиатскому типу B (до мутации) у европейцев был иммунитет.

Тип А разный в Китае и мире.

There are two subclusters of A which are distinguished by the synonymous mutation T29095C. In the T-allele subcluster, four Chinese individuals (from the southern coastal Chinese province of Guangdong) carry the ancestral genome, while three Japanese and two American patients differ from it by a number of mutations.

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>В Испании и Франции косит как раз В


В Европе не В, а только мутировавшие от него линии.

"For type B, all but 19 of the 93 type B genomes were sampled in Wuhan (n = 22), in other parts of eastern China (n = 31), and, sporadically, in adjacent Asian countries (n = 21).
Outside of East Asia, 10 B-types were found in viral genomes from the United States and Canada, one in Mexico, four in France, two in Germany, and one each in Italy and Australia. Node B is derived from A by two mutations: the synonymous mutation T8782C and the nonsynonymous mutation C28144T changing a leucine to a serine.

Cluster B is striking with regard to mutational branch lengths: While the ancestral B type is monopolized (26/26 genomes) by East Asians, every single (19/19) B-type genome outside of Asia has evolved mutations."


И тип С не обнаруживают на материковом Китае:

"Type C differs from its parent type B by the nonsynonymous mutation G26144T which changes a glycine to a valine. In the dataset, this is the major European type (n = 11), with representatives in France, Italy, Sweden, and England, and in California and Brazil. It is absent in the mainland Chinese sample, but evident in Singapore (n = 5) and also found in Hong Kong, Taiwan, and South Korea."